EXPERIMENTAL STUDY OF NOCARDIOSIS IN GUINEA PIGS

Article Sidebar

2000.2.18
Published: Dec 28, 2000
DOI: https://doi.org/10.30539/ijvm.v24i2.1180
Keywords:
GUINEA PIGS, NOCARDIOSIS

Main Article Content

M. J. ALWAN
Department of Vet. Pathology and poultry, College of Vet. Medicinę University of Baghdad, Iraq.

Abstract

The pathology of local isolated strain of Nocardia asteroides was study in pigs . 60 animals were divided into two groups. The 1st group (40 animals) was given a single intrapulmonary of 3.3X10'CFU of N. astoroides. The 2 nd group (20 animals) served as control . Eight animals died during the first 3 weeks post – infection while the remaining were sacrificed at 6, 12, 24, 48 hrs and 4, 8, 16, 24 and 62 days P.I. Early pathological examination revealed acute suppurative changes which seen turned into disseminated chronic form. Pyogranul matous and epithelioid granuloma have represented the main pathological changes at 8-24 days P.J. The results revealed arisein the level of bacterial counts followed by drop in count within 8-24 days P.I. Excepted kidney in which high bacterial counts persisted toward the end of the experiment

Downloads

Download data is not yet available.

Article Details

How to Cite
EXPERIMENTAL STUDY OF NOCARDIOSIS IN GUINEA PIGS. (2000). The Iraqi Journal of Veterinary Medicine, 24(2), 251-268. https://doi.org/10.30539/ijvm.v24i2.1180
Issue
Vol. 24 No. 2 (2000): Iraqi J Vet Med
Section
Articles

 

 

How to Cite

EXPERIMENTAL STUDY OF NOCARDIOSIS IN GUINEA PIGS. (2000). The Iraqi Journal of Veterinary Medicine, 24(2), 251-268. https://doi.org/10.30539/ijvm.v24i2.1180
Crossref
Scopus
Google Scholar
Europe PMC

References

1-Walton , A.M. and Libke , K.G. (1974) Nocardiosis in animals V.M.S. Ass. 69: 1105-1107.
2-Gordon, R.E. (1974) erobic pathogen actinomyetacea . Manual of clinical microbial . 2 nd . Washington PP. 176.
3-AL-Kafajy , S.A. (1994) Experimental pathological study of Nooardia asteroides in guinea pigs .M.S. Thesis , University of Baghdad.
4-Lwan ,M.J. (1990) Nocardia asteroides : studies on some aspeets of pathogenesis . Ph.D. Thesis University of Baghdad.
5-Miller, A.A.; Misra , S.S. and Irwin ,J. (1938) The estimation of bactericidal power of blood. J. Hyg. 38: 382-740.
6-Hiramine , J.A.; Stinson, E.B. and Koehne, R.C. (1985) Resistance to infection with N. asteroides J.Infect. Dis. 133 : 448-450 .
7-Floba , P.I.; Jaffe, R. and Altma , G. ( 1976) N. asteroides and N. brasiliensis infection in mice. Infect . Immun. 13:1490-1496 .
8-Jubo , K.V.F.; Kennedy , P.C. and palmer, N. (1985) Pathology of domestic animals. 3 rd. edition. Volume 2. P. 474.
9-Kissone , J.M. (1990) Andersons pathology , 9 th . Edit. Vol. I.P. 420.
10-Dennenberg , A.M. (1984) Cellular hypersensitivity and cellular immunity in the pathogenesis of tuberculosis specificity systemic and nature and associated macrophage enzymes . Bacteriol. Rev. 32: 85-102.
11-Davis, P. Allison , A.C. (1975) Secretion of macrophages enzymes in relation to the pathogenesis of chronic inflammation . Immunobiology of the macrophage edited by Nelson, D.S. Newyork . Aeademic press . Inc. P.428-463.
12-Miller, H.L.K.; Ninden , P. and Reynold, S.B.(1984) The role of cell wall associated in the pathogenesis of lesions in experimantal murine nocardiosis vs lesions produced by mycobacterium fortuilum . Comp. Immun. Microb. Infect. Dis. 7: 109-124.
13-Adam, D.O. (1976) The granulomatous inflammatory response Am. J.Path. 84: 164-191. 14-Beaman, B.L. and Maslan, S. (1977) The effect of cyclo- phosphamide on experimental N. asteroides infection in mice. Infect. Immun. 16: 833-846