COMPARISON BETWEEN THE EFFICACY OF 9 % HYPERTONIC SODIUM CHLORIDE SOLUTION, PENTOSTAM AND SILVER NITRATE FOR TREATMENT OF CUTANEOUS LEISHMANIASIS MOHAMMED A. KADIR AND HAYDER A. EL-GORBAN

Abstract

The study was conducted on 107 patients of cutaneous leishmaniasis, from
Dour town, Salahadeen province attending the Dermatology Department of
Saddam General Hospital, Tikrit.
Patients were divided to 4 groups for purpose of treatment and comparison,
followed up for two months duration.
Group A: treated with intralesional hypertonic sodium chloride solution (9 %
HSCS).
Group B: treated with intralesional pentostam injection, 1 cc. per day for 6
consecutive days.
Group C: treated with silver nitrate cauterization one to two doses of three days
interval.
Group D: left without treatment as a control group.
It was found that the efficacy of 9% hypertonic sodium chloride solution and
pentostam were 94% and silver nitrate was 78%. No patient cured among
untreated control group.
It was concluded that the efficacy of sodium chloride solution and pentostam
was greater than silver nitrate solution.