Astudy of some aspects of reproductive Performance in rabbits treated with Hydrocortisone
Article Sidebar
Main Article Content
Abstract
This experiment was carried out to study the changes in some of the structural – functional and biochemical aspects that are related to reproductive performance as a result of using glncocorticoid - hydrocortisone. Twelve adult male rabbit were divided into two equal groups : control and treatment. During pretreatment period ( Five days) blood samples were collected from all animals on every other days . During the treatment period (14) days each animal of the treatment group was injected daily , intramuscularly with hydrocortisone . Rabbit of the control group were injected with the same dose of normal physiological saline. Blood samples were collected as described above until (48) hours after last injection . All animals were scarified and samples from testicular tissue were taken to study structural – functional aspect.
Statistical analysis showed significant (P < 0.05) decrease in plasma testosterone of hydrocortisone treated rabbits, plasma levels of ICSH of both treatment and control groups of rabbits were parallel to each other (P< 0.05).
Downloads
Article Details
How to Cite
References
2- Scott, D.W. (1980). Feline dermatology 1900-1978 : J. Am. Anim. Hosp. Assoc. 16:331-332.
3- Brightman, A.H. (1982). Opthalmicuse of glucocorticoid. The Vet. Clinics of North America Small Animal practics , 12: 33-39.
4- Robson, J. and Sharaf, A. (1952). Effect of adrenocorticotrophic hormone (ACTH) and cortisol on pregnancy. J. physiology., 116: 236-243.
5- Jackson, P.G.G. (1979). Dystocia in heifers following induction of parturition using corticosteroids . Vet. Rec. 104 : 75. (Bet. Bull. , 49, 1979, Abst. No. 4848.
6- Catt, K.J. ; Tsuruhara, T.; Mendelson, C.; Ketelslegers, J.M. and Dufan, M.L. (1974) . Gonadotrophin binding and activation of interstitial cells of the testes. Curr. Top. Melec.
Endocrinol , 1: 1-30. Cited by Franchimount, 1983).
7- Ambine , T.H. and Hsueh , A.J.W. (1981). Direct inhibititory effect of glucocorticoids upon testicular LH receptor and steriodogensis in vivo and vitro. Endocrinol ., 108: 2142 -2148.
8- Desjardins , C. and Ewing, L.L. (1971) . Testicular metabolism in a drenalectomized and corticosterone treated rats. Proc. Soc. Exp. Biol. Med. 137: 578-583.
9- Vergans, H.L. and Eik-Nes, K.B. (1975). Hypothalmic pituitary – testicular system and adrenocortical function. Acta endocrinol , 81: 198-207.
10- Doerr, P. and Pirke, M. (1976) . Cortisol – induced suppression of plasma testosterone in normal adult males. J. clin. Endocrinol Metab., 4: 622-629.
11- Albert, A. (1961). The mammalian testis in : Young, W.C. sex and internal secretions. Third edition Vol. 1. The William and Wilkins Co.
12- Mehdi, A.W.R.; Al- Jiboori , N.A.; Al- Shathier, N.M. and Injidi, M. (1980) . Effect of a synthetic glucocorticoid on sexual behaviour and semon characteristics of ram. The 146th National meeting of the American Association for the Advancement of science .
13- Hanson, V.; Weddinton, S.C.; French , F.S.; Mclean, W.; Smith, A.; Nayfeh, S.N.; Ritzen, R.M. and Hagenas, L. (1997). Secretion and role of androgen – binding proteins in the testis and epididiymes . J. Reprod. Fertil., Suppl. 24: 17 33.