Experimental Pathological Study of Nitrate Toxicity in Broilers

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Raghad N. Al-saadi
Imad I. Al-Sultan

Abstract

This study was aimed to understand the chronic pathological change which is produced after potassium nitrate intake via water and food to broiler chicks for six weeks and in different concentrations also after 


stoppage for four weeks of nitrate intake. 135 chicks one day old fabrow breed were used, after two weeks aclimazation, chicks separated in to seven groups, one was control and 


the other six were given potassium nitrate in drinking water or in food in concentration 0.25, 0.5, 0.75 gm/kg of the body weight to each 


group. Gross and histopathological changes were studied, the pathological alteration characterized by gastritis of true stomach with metaplasia of gastric mucosa and chronic enteritis. Hepatic cell degeneration and necrosis .kidney showed congestion, haemorrhage and nephrosis. The thyroid gland was atrophied and the spleen was active due to hyperplasia of lymphoid cells and germinal centers. There was increase in the size of the lung which showed microscopically interstitial pneumonia, the brain was grossly soft and congested and microscopically there was degeneration of purkinge cell and increase 


neuromicroglial cells infiltration.

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How to Cite
Experimental Pathological Study of Nitrate Toxicity in Broilers. (2004). The Iraqi Journal of Veterinary Medicine, 28(1), 22-31. https://doi.org/10.30539/ijvm.v28i1.1089
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How to Cite

Experimental Pathological Study of Nitrate Toxicity in Broilers. (2004). The Iraqi Journal of Veterinary Medicine, 28(1), 22-31. https://doi.org/10.30539/ijvm.v28i1.1089

References

1. منظمة الصحة العالمية ،1989، دلائل جودة مياه الشرب ، الجزء الثاني للمعايير الصحية و معلومات مساعدة أخرى، المكتب الإقليمي لشرق البحر المتوسط،
الإسكندرية، مصر.
2. Nitrate Elimination Co., Inc., (2000), Nitrate: health risk to consurners.1-888-Nitrate (1-888-648-7283).
3. Hill, M.J., Hawksworth, G., and Tattersall, G. (1973). Bacteria, nitrosamines and cancer of the stomach. British J.cancer, 28:562 67.
4. Rasby, R.; stock Anderson, B.; Schneider, N. (1996).Nitrate in live stock Feeding. Cooperative extension, Institute of Agriculture and Natural Resources, University of Nebraska, Lincoln, G74-170A.
5. Luna, H.T.and Lee, G.(1968), Manual of histological staining method of the armed forces . Institute of pathology .310 .ed. The Blakistion Division McGraw-Hill Co. New York, Toronto,
London, Sydney.
6. Radostits, O.M.; Blood, D.C.and Gay, C.C. (1997). Veterinary medicine, A text book of the disease of Cattle, Sheep, Pigs, Goats and horses. 8th ed. W.B.Saunders Co., pp. 1536-1539.
7. السلطان ، عماد إبراهيم ، محمود،حافظ إبراهيم :علم أمراض الحيوان 1999 ، مطبعة جامعة الموصل ، وزارة التعليم العالي و البحث العلمي .
8. Owens, F.N., and Dubeski, P. (1992). Nitrate toxicity in ruminants, The National Dairy Database, Oklahoma, FF 121900.
9. Anderson, J.R. (1985). Muir's text book of pathology. 12th ed., printed by Edward Arnold Publishers Ltd., London.
10. Whitehead, J.E. (1953). Potassium nitrate poisoning in a dog -A case report.J.Amev. Vet.Med. Assoc. 123:232-233.
11. Al-aboudi, A.R. (1999). Pathology study of experimental nitrate toxicosis in chickens. Iraqi journal of Vet. Med.Sci. 2(12):341-345.
12.Jubb, K.V.F.; Kennedy, P.C.and Palmer, N.(1985). Pathology of domestic animals. 3rd ed. Academic Press Inc., Orland, London, Sydney, Toronto , Tokyo, New York, San Diego,Boston,pp.376.
13.Bruin, A.D. (1976). Bio chemical toxicology of environment Agents. Elsevier -North Holland .Bio chemical press.
14.Little Field, L.H.; Coursey, C.W. (1977). Influence of drinking water nitrate on heamatocrite, thyroid size, serum xan trophy, and pigmentation. Poult.Sci.56 (5):1731.
15. Parasad, J. (1983), Effect of high nitrate diet on thyroid glands in goats. Indian J.of Anim. Sci.35 (7)791-794.
16.Abdul-razzaq, H.A. (1992). The effect of nitrate in drinking water on liver function in laying hens. Iraq J.Vet.Med. 16:30-40.

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