Effect of Enrofloxacin Drug on Duodenum Smooth Muscle Movement in Broiler
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Abstract
Twenty chicks at (45) days old were used and divided into two equal groups , one act as treatment (Baytril) dosed orally (10 mg/kg ) for 5 days, while the control group dosed with distilled water.
Duodenum was isolated in vi tro examined with autonomic agents.
The result showed significant decrease in intestinal motility between treatment and control group after addition of atropine, acetycholine, atropine flowed acetycholine and after addition propranolol and propranolol flowed adrenaline.
Concluded from this study that using of Enrofloxacin case a negative alteration tonic and rhythmic contraction of intestinal (smooth muscles).
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Effect of Enrofloxacin Drug on Duodenum Smooth Muscle Movement in Broiler. (2004). The Iraqi Journal of Veterinary Medicine, 28(1), 87-94. https://doi.org/10.30539/ijvm.v28i1.1069
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How to Cite
Effect of Enrofloxacin Drug on Duodenum Smooth Muscle Movement in Broiler. (2004). The Iraqi Journal of Veterinary Medicine, 28(1), 87-94. https://doi.org/10.30539/ijvm.v28i1.1069
References
1. Andona, A. ;Martinez, M. R. ; Diaz, M.J.; Bringas, P. Martinez, A. ; Fernadez, M.L. ; Fernadez, M.C. and Fernadez, Z. R. (1995) Pharmacokinetics and residues of Enrofloxacin in chickens. Am. J. Vet. Res., 56 (4) : 501 - 506.
2. Brown SA. (1996). Fluoroqinolones in animal Health. J. Vet. Pharmacol. Therap. 19: 1- 4.
3. FAO paper 41/7 (1995). Residues of Some Veterinary Drugs in Animal and Foods.
4. Ganong, (1995) Review of Medical Physiology. 16th edition. Long medical book prentice - Hall International Inc. P 56.
5. Giewbccz, M.A., Barnes, P.J. (1991). Selective inhibition of high affinity type IV Phosphor diestrase in bovin treachea and intestine by simple activity substrate, Biochem Pharmacol. 42: 663 – 667.
6. Henderson, A. (1995). Hepatotoxicity ciprofloxacin induced. Infectious Disease Weekly - 518: P23.
7. Katzung & Bertram G. (1995). Basic and Clinical Pharmacology. Sixth edition long medical book.
8. Neo, M. and Sharma, S. (2001). The effect of Quinolones and Teracyclen on nerve ending of scieitic nerve. J. Aus. Med. 7 (73): 92 - 97.
9. Nix, D.E., Wilton, J.H., Ronald, B. , Disteleath, L., Inhwilliams, V.C. & Norman, A., (1990). Inhibitory of Norfloxacin Absorption
Antiacids. Antimicrob. Agents and Chemother 34. 432 – 435.
10.Ovand, H. G.; Gorla, N.; Luders, C.; Errecalde, C.; prieto, G. and puelles, I. (1999). Comparative Ciprofloxacin in Chicken. J. Vet.
Pharmacol. Therap. 22: 209 - 212.
11. Rang, H.; Dale, M. and Ritter, J. (1995). Pharmacology, 3rd. Churchill & unigstone. P. 513.
12.Roscoe, I. ; Ibrhim, N. and Susan, F. (2001). Transcription factors and their inhibiter (Reviow) National process Academic science 6.1 (2) vol(7). P. 92.
13.Shah, P.M. & Mulert, R. (1990) Safety Profile of Quinolones. Eur. Urol. 17: 46 – 51 Abs.
14.Timmonas, K. and Sterglanz, R., (1978). Inonization and divalent cation dissociation constants of Nalidixic and oxolinic acid. Bionory. Chem.. 9: 145 - 155.
15. Winfield, A. J. and Richard, R.M. (1999) Pharmaceutical Practice 2nd, Churchill livingstone.
2. Brown SA. (1996). Fluoroqinolones in animal Health. J. Vet. Pharmacol. Therap. 19: 1- 4.
3. FAO paper 41/7 (1995). Residues of Some Veterinary Drugs in Animal and Foods.
4. Ganong, (1995) Review of Medical Physiology. 16th edition. Long medical book prentice - Hall International Inc. P 56.
5. Giewbccz, M.A., Barnes, P.J. (1991). Selective inhibition of high affinity type IV Phosphor diestrase in bovin treachea and intestine by simple activity substrate, Biochem Pharmacol. 42: 663 – 667.
6. Henderson, A. (1995). Hepatotoxicity ciprofloxacin induced. Infectious Disease Weekly - 518: P23.
7. Katzung & Bertram G. (1995). Basic and Clinical Pharmacology. Sixth edition long medical book.
8. Neo, M. and Sharma, S. (2001). The effect of Quinolones and Teracyclen on nerve ending of scieitic nerve. J. Aus. Med. 7 (73): 92 - 97.
9. Nix, D.E., Wilton, J.H., Ronald, B. , Disteleath, L., Inhwilliams, V.C. & Norman, A., (1990). Inhibitory of Norfloxacin Absorption
Antiacids. Antimicrob. Agents and Chemother 34. 432 – 435.
10.Ovand, H. G.; Gorla, N.; Luders, C.; Errecalde, C.; prieto, G. and puelles, I. (1999). Comparative Ciprofloxacin in Chicken. J. Vet.
Pharmacol. Therap. 22: 209 - 212.
11. Rang, H.; Dale, M. and Ritter, J. (1995). Pharmacology, 3rd. Churchill & unigstone. P. 513.
12.Roscoe, I. ; Ibrhim, N. and Susan, F. (2001). Transcription factors and their inhibiter (Reviow) National process Academic science 6.1 (2) vol(7). P. 92.
13.Shah, P.M. & Mulert, R. (1990) Safety Profile of Quinolones. Eur. Urol. 17: 46 – 51 Abs.
14.Timmonas, K. and Sterglanz, R., (1978). Inonization and divalent cation dissociation constants of Nalidixic and oxolinic acid. Bionory. Chem.. 9: 145 - 155.
15. Winfield, A. J. and Richard, R.M. (1999) Pharmaceutical Practice 2nd, Churchill livingstone.