Morphological Study of The Pancreas and Duodenum in Adult Guinea Pigs (Cavia porcellus)
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Abstract
The present study aimed to investigate the morphological features of the pancreas and duodenum of the adult males and females guinea pigs. Eight animals of each sex were collected to conduct this project. The selected organs were photographed in situ and macro morphometric measurements were conducted on them. Gross findings revealed that the pancreas of guinea pig was of compact type, of two lobes (right and left) connected by large central part (body). The organ drains the pancreatic secretion toward the last part of the ascending duodenum via minor pancreatic duct with absence of major pancreatic duct. The duodenum of the guinea pig was very short and V-shaped. The beginning of the duodenum contains duodenal papilla in which found central orifice for the exit of bile secretions of the common bile duct. In conclusions, the present findings showed the presence of only one minor pancreatic duct and such result was significantly different than most rodents by having major pancreatic duct. The duodenum in the studied guinea pigs was characteristically very short and V-shaped differently to other animals that have U-shaped and long duodenum.
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Kunzl C and Sachser N. The behavioural endocrinology of domestication: a
comparison between the domestic guinea pig (Cavia aperea f. porcellus) and its wild
ancestor, the cavy (Cavia aperea). Horm. Behav. 1999; 35: 28-37.
North D. The guinea pig. seventh ed. Pool, T. The UFAW Handbook on the Care and Management of Laboratory Animals, 1. Blackwell Science, Ltd., London, 1999; pp. 367-388.
Guo Y, Bao Y, Meng Q, Hu X, Meng Q, Ren L, Li N, Zhao Y. Immunoglobulin genomics in the guinea pig
(Cavia porcellus). PLoS ONE, 2012; 7(6): e39298
Al-Haaik AG, Al-Saffar FJ. Morphological and histomorphometrically study of the Sacculu rotundas at
different postnatal ages in indigenous rabbit. Iraqi JVM.,2017;41(1):131-7
Seymour PA, Bennett WR, Jonathan MW, Slack JM. Fission of pancreatic islets during
postnatal growth of the mouse. J. Anat., 2004; 204: 103-16.
Isitor GN, Rao S, Nayak SB, Sundaram V. Auto fluorescent vesicular structures in hematoxylin and eosin stained duodenal mucosa of the domestic cat. West Indian Vet. J., 2009; 9 (2): 27-32.
Daniaux LA, Laurenson MP, Marks SL, Moore P F, Taylor SL, Chen RX, Wingenberger AL Ultrasonographic thickening of the muscularis propria in feline small intestinal small cell T -cell lymphoma and inflammatory bowel disease. J. Feline Med. Surg., 2014; 16(2): 89–98.
Takeuchi Y, Takahashi M, Tsuboi M, Fujino Y, Uchida K, Ohno K, Nakayama H, Tsujimoto H. Intestinal T-cell lymphoma with severe hyper eosinophilic syndrome in a cat. J. Vet. Med .Sci., 2012; 74(8): 1057–62.
Bossche VD, Paepe D, Daminet S. Acute pancreatitis in dogs and cats: pathogenesis, clinical signs and clinicopathologic findings.Vlaams Diergeneeskundig Tijdschrift, 2010; 79: 13-22.
De Cock HEV, Forman MA, Farver TB, Marks SL. Prevalence and histopathologic
characteristics of pancreatitis in cats. Vet. Pathol., 2007; 44: 39–49.
Louwerens M, London CA, Pedersen NC, Lyons LA. Feline lymphoma in the post-feline leukemia virus era.
J. Vet. Intern. Med., 2005; 19: 329–35 .
Saluja A, Meldolesi J, Teer M. Pancreatic duct obstruction in rabbits causes digestive
zymogene and lysosomal enzyme colocalization. J. Clin. Invest., 1989; 84(4): 1260-1266.
Eifler AC, Lewandowski RJ, Virmani S, Chung JC, Wang D, Tang RL, Kowalska BS, Woloschak GE, Yang GY, Robert K, Ryu RK, Salem R, Larson AC, Cheon E, Strouch M ,Bentrem DJ, Omary RA. Development of the VX2 pancreatic cancer model in rabbits: A platform to test future interventional radiology therapies.
J. Vasc. Interv. Radiol., 2009; 20 ( 8 :) 82-1075.
Kara ME. The anatomical study on the rat pancreas and its ducts with emphasis on the
surgical approach. Ann. Anat., 2005; 187: 105-12.
Al-Saffar FJ, Al-Hasnawy AHA. Histomorphological developmental study of advanced postnatal of the pancreas of local rabbit. J. Biol. Sci., 2014; 14: 387-402.
Tsuchitani M, Sato J, Kokoshima H. A comparison of the anatomical structure of the pancreas in
experimental animals. J. Toxicol Pathol., 2016; 29: 147–54.
Al-Saffar FJ, Al-Zuhairy MF. Postnatal developmental micromorphological and histochemical study of the pancreas in the domestic cat. Int. J. Adv. Res., 2017; 5: 55-71.
Dintzis SM, Liggitt D. Chapter 14: Pancreas. In: Treuting PM, Dintzis SM, Frevert CW ,
Liggitt D, Montine KS. Comparative anatomy and histology. London, UK: Elsevier
Academic, Press. 2012; 203-9.
Catala J, Bonnafous R, Dutrillaux MC, Hollande E. Dissociation of Langerhans islets in the rabbit after pancreatic duct ligation. Cell Pathol., 1987; 52: 539-51.
Elayat AA, El-Naggar MM, Tahir M. An immunocytochemical and morphometric
study of the rat pancreatic islets. J. Anat., 1995; 186: 629-37.
Slack J. Developmental biology of the pancreas. Development, 1995; 121(6): 1569-80.
Dyce K M, Sack WO, Wensing CJG. Textbook of veterinary anatomy, 2nd edition, 1996 ;W.B. Saunders Company, Philadelphia
Al-Saffar FJ, Al-Zuhairy MF. Postnatal developmental histomorphological and
histochemical study of the duodenum in the domestic cat. Int. J. Curr. Res., 2016; 8 43681 -09.
Brewer N. Biology of the rabbit. J Am Assoc Lab Anim., 2006; 45(1): 8-24.
Davies RR, Davies JAER. Rabbit gastrointestinal physiology. Vet. Clin. Exot. Anim., 2003 ;(6):139-53.
Treuting PM, Valasek MA, Dintzis SM. Upper gastrointestinal tract. In comparative anatomy and
histology: A mouse and human atlas (P. M. Treuting and S. M. Dintzis, eds.), 1st ed, 2011 p. 167.
Academic press, Elsevier Inc, New York.
Tsuji K, Yang M, Jiang P, Maitra A, Kaushal S, Yamauchi K, Katz MH, Moossa AR ,
Hoffman RM, Bouvet M. Common bile duct injection as a novel method for establishing red
fluorescent protein (RFP)-expressing human pancreatic cancer in nude mice. JOP, 2006; 7: 193-199.
Mooren FC, Hlouschek V, Finkes T, Turi S, Weber IA, Singh J, Domschke W,
Schnekenburger J, Krüger B, Lerch MM. Calcium signaling after pancreatic duct early
changes in pancreatic acinar cell obstruction. J. Biol. Chem., 2003; 278: 9361-9.
Murray KA. The laboratory rabbit, guinea pig, hamster, and other rodents. Chapter 27 :
Anatomy, physiology and behavior, 2012; 753-63.
Witchtel MEG. Studies on the control of exocrine pancreatic secretion in the dog. A thesis present in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Massey University, 2002.
Nath SK, Das S, Kar J, Afrin K, Dash AK, Akter S. Topographical and biometrical anatomy of the digestive
tract of White New Zealand Rabbit (Oryctolagus cuniculus). J. Adv. Vet .Anim. Res., 2016; 3(2): 145-51.