Biochemical study on the effect of Toxoplasma gondii on Liver function in Women
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Abstract
The aim of this study was to detect the effect of toxoplasmosis on some liver enzyme activity
such as bilirubin concentration, Alanine aminotransferase (ALT), Aspartate aminotransferase
(AST), Alkaline Phosphatase (ALP) in serum. Twenty hundred and fifty women were examining
by Enzyme-linked immunosorbent assay (ELISA). One hundred and thirty-four were infected with
toxoplasmosis with different number of abortion (1-4) times were used in this work. All Serum
ALT and AST activities were increased and ALP and total bilirubin level decreased in infected
women below the normal value. The analysis of the plasma enzyme distribution pattern suggests
that liver cell damage occurred during virulent and low virulent infection, leads to be inflated cells
as provided and expansion in Central necrosis of hepatic veins and damage in various parts of the
liver
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