Study on blood gases, Acid-Base balance and the therapeutic evaluation of different protocol of treatment of mastitic cows

Abstract

This study was planned to reveal the changes in blood gases and acid-base
values in mastitic cows and to state the intravenous fluid therapy regimen
treatment. A herd with a population of 150 lactating cows was screened for
clinical and subclinical mastitis for a period of 6 months. Based on inclusion and
exclusion criteria, twenty-eight cows with clinical mastitis were divided in three
groups (mastitic not treated (group M), mastitic treated with antibiotic only
(group TA) and mastitic treated with antibiotic and fluid therapy (group TAF)
and another five healthy cows (group C) served as controls. Blood gases, SCC,
CMT scores, udder health status and cure rate were carefully investigated. There
was significant differences between PO2, PCO2, BE, and HCO3
-concentration in
mastitic cows. Increased pH, BE, and HCO3
- referred to metabolic alkalosis
whereas increased PCO2 indicate compensatory respiratory acidosis. The results
of SCC in milk agreed to CMT scores, and to some extent to udder health status
among the entire period of study. Cure rate was earlier in group TAF with less
number of treatment than in group TA. It has been concluded from this study
that administration of fluid therapy might be useful as an adjunct in case of
clinical mastitis in cows to get quick clinical recovery with less number of
treatments. However, the role of blood gases and acid – base status in mastitis
should be investigated in details.