Comparative therapeutic studies on experimentally infected mice and naturally infected calves with ringworm Ouroba, M.S. brahim ,Saadi, A. G.Al-Samarrae and Jenan,M.K. Najim

Abstract

Groups of mice experimentally infected with ringworm Trichophyton mentagrophyte were treated with
ointments prepared from 5% cold alcoholic extract of two plants of Thymbra spicata , Ruta chalepnsis
and compared with the commercial drug “Clotrmazole” (1%), recovery from ringworm needed 16 , 18 ,
14 days for Th.spicata, Ruta chalepensis and Coltrmazole respectively.
On the other hand 28 naturally infected calves with ringworm from the genera Trichophyton
mentagrophytes and Aspergillus were divided into four groups, and each group treated individually with
one of the ointments 5% concentration , cold alcoholic extract of Th.spicata and Ruta chalepensis beside
“Clotrimazole”.The fourth group was left as a positive control group
Recovery from ringworm was complete after 21, 25, 18 days in the groups treated with spicata, Ruta
chalepensis and “Clotrimazole respectively. These results indicate the therapeutic effect of the cold
alcoholic extract of the two plants used compared to commercial antifungal drug