EFFECT OF OXYTOCIN AND BROMOCRIPTINE ON CORPORA LUTEA AND PSEUDOPREGNANCY IN MICE
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Abstract
Oxytocin adminstered on the fifth day of pseudopregnancy daily at a dose of 200 mU for 4 days, caused. an extension in pseudopregnancy length. Concomitant adminstration of bromocriptine (10 mg) caused reduction in pseudopregnancy length. Ovarian and uterine changes associated with oxytocin adminstration included: an increase in weight and percentage of active corpora lutea in animals sacrificed 48 and 72 hours post treatment.
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Sheldrick, E.L. and Flint, A.P.F. (1981). Circulating concentrations of oxytocin during the estrus cycle and early pregnancy in sheep. Prostaglandins. 22: 631-636.
Wathes, D. C. and Swann, R.W. (1982). Is oxytocin an ovarian hormone? Nature (London). 297: 255-227.
Harrison, L.M., Kenny, N. and Niswender, G.D. (1987). Progesterone production, LH receptors and oxytocin secretion by ovine luteal cell types on days 6, 10 and 15 of the oestrus cycle and day 25 of pregnancy. J. Reprod. Fert. 79: 539-548.
Schams, D., Kruip, Th. A. M. and Kol1, B. (1985) . Oxytocin determination in steroid production tissues and in vitro production in ovarian follicles. Acta Endocrinol. (Copenh.). 109: 530-536.
Hansel, W. and Wagner, W.C. (1960). Luteal inhibition in the boving as a result of oxytocin injection, uterine dilatation and intra uterine infusion of seminal and preputial fluids. J. Dairy Sci. 43:796-805.
Anderson, L.L., Bowerman, A.M. and Melampy, R.M. (1965). Oxytocin on ovarian function in cycling and hysterectomized heifers. J. Anim. Sci. 24: 964-968.
Flint, A.P.F., Mitchell, M.D. and Sheldrick, E.L. (1979). Delayed luteal regression in ewes immunized against oxytocin. J. Physiol. 269: 85-86.
Snedecor, G.W. and Cochran, W.G. (1967). Statistical methods. 6th edition. The lowa State College Press, Ames, Iowa.
Hilliard, J. (1973). Corpus luteum function in guinea pigs, hamesters, rats, mice and rabbits. Biol. Reprod. 8:203-221.
Nalbandov, A.V. (1976). Reproductive physiology of mammals and birds. 3rd edition. Freeman and company, San Fransisco.
Garland, H.O., Atherton, J.C., Baylis, C., Morgan, M.R.A. and Milne, C.M. (1987). Hormones profiles for progesterone, and oestradiol, prolactin, plasma renin activity, aldosterone and corticosterone during pregnancy and pseudopregnancy in two strains of rats: correlation with renal studies. J. Endocrinol. 113: 435-444.
Thorner, M.O., Fluckiger, E. and Clane, D.B. (1980) Bromocriptine, a clinical and pharmacological review. Raven Press, New York.
Tan, G.J.S., Tweedale, R. and Biggs, J.S.G. (1982a). Oxytocin may play a role in the control of the human corpus luteum. J. Endocrinol. 95: 65-70.
Tan, G.J.S., Tweedale, R. and Biggs, J.S.G. (1982b). Effects of oxytocin on the bovine corpus luteum of early pregnancy. J. Reprod. Fert. 66:75-78.
Wathes, D.C. (1984). Possible actions of gonadal oxytocin and vasopressin. J. Reprod. Fert. 71:315-345.
Redmond, A.F. and Pepe, G.J. (1986). Uterine progesterone metabolism during early pseudopregnancy in the rat. Biol. Reprod. 35: 949-955.
Al-Janabi, A.S. and Yousif, W.H. (1987). Changes in ovarian function associated with oxytocin injection to immature rate. Ann. Rech. Vet. 18:58-61.