VACCINATION OF CALVES WITH LIVE MODIFIED AND LIVE VIRULENT STRAIN OF SALMONELLA TYPHIMURIUM

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F G Habasha

Abstract

Sixteen normal colostrum-fed -Friesian and Holestein-Friesian X Angus crossbred calves, ranging in age from 2 to 7 weeks were divided into 4 vaccinated groups and 1 nonvaccinated (control) group. Group I consisted of 2 calves vaccinated orally twice at a two week interval with small doses of organisms ( 104 thar1l05 live virulent Salmonella gghimurium, strain 108-11). Group ll consisted of 2 calves vaccinated orally twice at two weeks interval with 1011 organisms (modified Salmonella typhimurium, strain SL 3261 ). Group [[1 consisted of 2 calves vaccinatedlivitwice at two weeks interval with small doses of organisms ( 104 than 105 virulent Salmonella typhimurigg, strain 108-11). Group IV consisted of 3 calves which were vaccinated 1M twice atv/o weeks interval with109 live modified strain 108-11(SL 1479). Group V consisted of 7 calves which served as nonvaccinated controls. One to two weeks after the final vaccine close all calves were orally challenge exposedwith 1.5x 1011 viable Salmonella typliimurium, strain 108-11. The results of vaccination with different preparation of vaccine indicated that a modified live vaccine strain designated as SL 1479 with complete, nonreverting blocks in aromatic biosynthesis may beappropriate for protecting domestic animals against Salmonella infection.

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How to Cite
VACCINATION OF CALVES WITH LIVE MODIFIED AND LIVE VIRULENT STRAIN OF SALMONELLA TYPHIMURIUM. (1996). The Iraqi Journal of Veterinary Medicine, 20(2), 112-131. https://doi.org/10.30539/ijvm.v20i2.1365 (Original work published 2022)
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How to Cite

VACCINATION OF CALVES WITH LIVE MODIFIED AND LIVE VIRULENT STRAIN OF SALMONELLA TYPHIMURIUM. (1996). The Iraqi Journal of Veterinary Medicine, 20(2), 112-131. https://doi.org/10.30539/ijvm.v20i2.1365 (Original work published 2022)

References

*Gibson,E.A.(1965). Review of the progess of dairy science section E.Diseases of dairy cattle. Salmonella infectionin

cattle. J.Dairy Research, 32:97 -134.

*Smith,B.P.; I-Iabasha,F.G.,; Reina.-Guerra.,M,;Hardy,A.J.(l980).Immunization of calves against Salmonellosis. Am.J. Vet. Res. 41:1947-1951.

*Haisetl1,S.K. and Stocker,B.A.D.(1981). A complete block in aromatic biosynthosis makes _S_. tmhimurium- non virulent vaccine. Nature 2911238-239.

*Hsu,H.S.;Ma.ye,D.R.(1973). Interactions between macrophages of guinea pigs and Salmonella DI. Bacterial action and cytolpan

antibodies of macrophages of infected guinea pigs. Infection and Immunity 8:165~172.

*Wray,C.,Sojl

*Smith,B.P., Habasha.,F.G.,Reina-Guerra,M. and Hardy, A.J. (1979). Bovine Salmonellosis experimental production and characterization of the

disease in calves, using oral challenge with Salmonella typliimurium . Am..I.Vet.Res. 40:1510-1513.

*Smith,H.W.(1’965). The Immunization of mice, calves and pigs against Salmonella dublin and Salmonella cholerasuis infection. J.Hyg. (Comb) 63: 117-13 5 .

*RanKin,J.D.;Newma,G. and Tayler,R.J.(1966). The protection of calves against infection with Salmonella typhimurium by means of S_. dublin (Strain 51 ) vaccine Vet.Rec.78:765-766.

*Cameron,C.M. and Fuls,W.S.P.(1976). Immunization of mice and calves against Salmonella dublin with attenuated live and inactivated vaccine. Onderstepoo